Apotex Inc. has formulated their pharmaceuticals to contain the exact same chemical and to produce the same beneficial effects as the original brand name products they replace. The testing methods employed in Canada are some of the most rigorous used anywhere in the world and they incorporate bioequivalence studies comparing the two products. Proof that the Apotex product is equivalent to the originator's product is provided by the Therapeutics Products Program of Health Canada, the Canadian Regulatory Agency, in their declaration of equivalence.

A typical example of the result of a bioequivalence study is illustrated in the following graph, which shows the concentration of the drug in the serum at each point in time, comparing the originator's brand in red with the Apotex brand in blue. Once the active drug is circulating in the body, all brands will perform the same at the same concentration.

Bioeqivalence Graph